Specific recurrent fusions validated included BCR-ABL, CCDC6-RET, and PML-RARA.
This research suggests that degron loss is a general mechanism in tumorigenesis, similar to promoter swapping, as shown in the study's PDF document . 24336.rar
Fusions involving known oncogenes often retain functional domains and are "in-frame," supporting their role in cancer, as noted in the Nature Communications study . Specific recurrent fusions validated included BCR-ABL