Transform the iconic "Spooky Island" or "Crystal Cove" into a literal Dark Forest. The "meddling kids" are the "loud civilizations" from the theory. By solving mysteries, they were making noise, drawing the attention of something much larger than a man in a rubber suit.
They are the only ones who see clearly. Their "cowardice" is actually the correct evolutionary response to a predatory universe. Their hunger is a primal distraction from the existential dread. IV. The Setting: The Forest that Listens
Velma represents Science. In the Dark Forest, her "clues" become meaningless. Her arc ends when she realizes that logic is a flashlight with dying batteries in an infinite cave.
His obsession with traps is a literal attempt to cage the unknown. His breakdown occurs when he realizes you cannot trap a shadow.