Download: Cerebral Amyloid Angiopathy Criteria The Next Generation Pdf

The "next generation" of cerebral amyloid angiopathy (CAA) diagnosis is defined by the , released in late 2022 to replace the 2010 modified criteria. This update shifts the diagnostic paradigm from purely hemorrhagic markers to a more holistic "small vessel disease" profile, integrating white matter signatures. Key Evolutions in the Next Generation Criteria

: While lobar intracerebral hemorrhage (ICH) and microbleeds remain central, cortical superficial siderosis (cSS) and convexity subarachnoid hemorrhage are now prioritized. Multiple separate foci of siderosis can now qualify a patient for a "probable CAA" diagnosis on their own. The "next generation" of cerebral amyloid angiopathy (CAA)

: Specific patterns of white matter damage. Clinical Significance Multiple separate foci of siderosis can now qualify

: Enlarged fluid spaces in the deep white matter. : The minimum age for applying the criteria

: The minimum age for applying the criteria has been lowered from 55 to 50 years .

The Boston criteria version 2.0 for cerebral amyloid angiopathy