: The album The 2nd Law reached number one in 13 countries and was nominated for Best Rock Album at the 55th Annual Grammy Awards. 2. Muse Cells: "Isolated System" in Medicine

"Isolated System" is the final track on Muse's 2012 studio album, The 2nd Law . It is a dark, atmospheric piece that prominently features news samples discussing the second law of thermodynamics and the concept of entropy.

In biology, "Muse" refers to . These are a recently discovered type of natural pluripotent stem cell found in adult human tissues like bone marrow and skin.

: Following the album's concept of a resource-strapped planet, the song uses the scientific principle of an "isolated system"—one that cannot exchange energy with its surroundings—to symbolize humanity's unsustainable path.

: The track gained significant popularity for its inclusion in the 2013 film World War Z . It serves as a haunting backdrop for the film's apocalyptic themes of global collapse and resource exhaustion.