Pearlcam -
Researchers use PearlCAM to test new "smart" dyes that attach specifically to cancer cells. By viewing the animal through the Pearl system, surgeons can practice identifying tumor margins that would be invisible to the naked eye. Washington University has utilized this for foundations in translational imaging. 2. Drug Delivery Tracking
A fluorescent probe (like IRDye®) is injected into the subject. PearlCAM
The workflow for a research team using PearlCAM typically follows three stages: Researchers use PearlCAM to test new "smart" dyes
The subject is placed in the imaging chamber. PearlCAM software captures the NIR signal and overlays it on a standard grayscale "white light" image for anatomical context. PearlCAM software captures the NIR signal and overlays
PearlCAM is the proprietary interface used to capture and analyze high-resolution images in the spectrum. Unlike visible light, NIR light can penetrate several centimeters into biological tissue, allowing for:
The software quantifies the signal intensity, allowing researchers to say exactly how much of a drug reached the target compared to healthy tissue. 🌟 Why It Matters
💡 Many researchers prefer the Pearl system because it uses a One-Touch imaging approach—eliminating the need for complex camera adjustments and making the technology accessible even to those without a background in physics.