Check the (or Unlocks) menu in-game. It acts as a roadmap.

Blue gems are worth the least, green are medium, and red/gold hold the most accumulated XP. If you see a red gem, go for it—it likely contains all the XP from enemies killed off-screen. Essential Weapon Evolutions

Creates a permanent spinning barrier that keeps enemies away. Soul Eater

Creates damaging zones that grow and follow you. Highest DPS in the game. Duplicator Thunder Loop High damage that strikes twice. Clears the screen quickly. The Meta-Progression (Spend Your Gold)

Never stay still. Enemies spawn in a circle around you. Move in a consistent direction or wide circles to "herd" them into a pack, making it easier to hit many at once.

To survive past the 20-minute mark, you evolve your weapons. To evolve, you need a Max Level weapon and at least one level of its "matching" passive item. Open a chest after the 10-minute mark to trigger the evolution. Base Weapon Passive Item Needed Evolved Form Why it’s good King Bible Spellbinder Unholy Vespers

Increases the chance of getting 3 or 5 items in a chest and better level-up choices.